MetaCyc Pathway: superpathway of phospholipid biosynthesis III (E. coli) in Escherichia coli HS(pFamp)R (ATCC 700891)

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Reactions and Genes iri MOI10
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Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) (in reverse):
glycerone phosphate + NAD(P)H + H+→sn-glycerol 3-phosphate + NAD(P)+ (EC 1.1.1.94)
OHPLBJKB_00091 N.D.
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-[acyl-carrier protein]→a 2-lysophosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.15)
OHPLBJKB_00645 +0.1
OHPLBJKB_02576 -0.3
OHPLBJKB_04002 N.D.
Glycerol-3-phosphate O-acyltransferase:
sn-glycerol 3-phosphate + an acyl-CoA→a 2-lysophosphatidate + coenzyme A (EC 2.3.1.15)
OHPLBJKB_00645 +0.1
OHPLBJKB_02576 -0.3
OHPLBJKB_04002 N.D.
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-[acyl-carrier protein]→a phosphatidate + a soluble [acyl-carrier protein] (EC 2.3.1.51)
OHPLBJKB_00684 N.D.
OHPLBJKB_04191 +0.3
1-acylglycerol-3-phosphate O-acyltransferase:
a 2-lysophosphatidate + an acyl-CoA→a phosphatidate + coenzyme A (EC 2.3.1.51)
OHPLBJKB_00684 N.D.
OHPLBJKB_04191 +0.3
Phosphatidate cytidylyltransferase:
a phosphatidate + CTP + H+→a CDP-diacylglycerol + diphosphate (EC 2.7.7.41)
OHPLBJKB_02305 +0.1
OHPLBJKB_03488 N.D.
OHPLBJKB_03489 N.D.
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase:
a CDP-diacylglycerol + sn-glycerol 3-phosphate→a phosphatidylglycerophosphate + CMP + H+ (EC 2.7.8.5)
OHPLBJKB_01817 N.D.
OHPLBJKB_02306 -0.2
CDP-diacylglycerol--serine O-phosphatidyltransferase:
a CDP-diacylglycerol + L-serine→a phosphatidylserine + CMP + H+ (EC 2.7.8.8)
OHPLBJKB_01121 N.D.
Phosphatidylglycerophosphatase:
a phosphatidylglycerophosphate + H2O→a phosphatidylglycerol + phosphate (EC 3.1.3.27)
OHPLBJKB_01147 -0.0
OHPLBJKB_02404 -0.2
OHPLBJKB_03258 -0.6
Phosphatidylserine decarboxylase:
a phosphatidylserine + H+→a phosphatidylethanolamine + CO2 (EC 4.1.1.65)
OHPLBJKB_03882 -0.4
2 a phosphatidylglycerol→a cardiolipin + glycerol (EC 2.7.8.41)
OHPLBJKB_02434 -1.8
OHPLBJKB_02924 -0.1
a phosphatidylethanolamine + a phosphatidylglycerol→a cardiolipin + ethanolamine (EC 2.7.8.41)
OHPLBJKB_02618 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information