MetaCyc Pathway: pyruvate fermentation to butanol II (engineered) in Acinetobacter radioresistens SK82

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Reactions and Genes L-tyrosine (C)
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Acetyl-CoA C-acyltransferase:
2 acetyl-CoA→acetoacetyl-CoA + coenzyme A (EC 2.3.1.16; 2.3.1.9)
MPMX26_00225 -0.3
MPMX26_00611 N.D.
MPMX26_00837 N.D.
MPMX26_01592 N.D.
MPMX26_01701 -1.0
MPMX26_01750 +0.0
MPMX26_02383 -0.9
MPMX26_02495 +0.0
3-hydroxyacyl-CoA dehydrogenase (in reverse):
acetoacetyl-CoA + NADH + H+→(S)-3-hydroxybutanoyl-CoA + NAD+ (EC 1.1.1.35)
MPMX26_00226 -0.6
MPMX26_00610 +0.6
MPMX26_01177 N.D.
MPMX26_03059 -1.7
(S)-3-hydroxybutanoyl-CoA→crotonyl-CoA + H2O (EC 4.2.1.150)
MPMX26_00226 -0.6
MPMX26_00534 +0.2
MPMX26_01501 N.D.
MPMX26_01546 N.D.
MPMX26_01555 N.D.
MPMX26_02179 +0.2
Trans-2-enoyl-CoA reductase (NAD(+)) (in reverse):
crotonyl-CoA + NADH + H+→butanoyl-CoA + NAD+ (EC 1.3.1.44)
MPMX26_01178 N.D.
MPMX26_01335 N.D.
MPMX26_01461 -0.0
MPMX26_01547 N.D.
MPMX26_01591 N.D.
MPMX26_01595 N.D.
MPMX26_01600 N.D.
MPMX26_01931 N.D.
MPMX26_02023 -0.0
MPMX26_02120 N.D.
MPMX26_02693 N.D.
Butanal dehydrogenase (in reverse):
butanoyl-CoA + NAD(P)H + H+→1-butanal + coenzyme A + NAD(P)+ (EC 1.2.1.57)
No genes
1-butanal + NADH + H+→butan-1-ol + NAD+
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information