MetaCyc Pathway: GABA shunt II in Escherichia coli BW25113

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Reactions and Genes Putrescine (N)
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Glutamate synthase (ferredoxin) (in reverse):
2-oxoglutarate + L-glutamine + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→2 L-glutamate + 2 an oxidized ferredoxin [iron-sulfur] cluster (EC 1.4.7.1)
No genes
Glutamate decarboxylase:
L-glutamate + H+→4-aminobutanoate + CO2 (EC 4.1.1.15)
b1493 (gadB) +0.1
b3517 (gadA) -0.2
4-aminobutyrate transaminase:
2-oxoglutarate + 4-aminobutanoate→L-glutamate + succinate semialdehyde (EC 2.6.1.19)
b1302 (puuE) -0.9
b2662 (gabT) -0.6
Succinate-semialdehyde dehydrogenase:
succinate semialdehyde + NAD+ + H2O→succinate + NADH + 2 H+ (EC 1.2.1.24)
b1300 (puuC) -5.3
b1525 (b1525) -0.6

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information