MetaCyc Pathway: spermidine biosynthesis II in Escherichia coli BW25113
| Reactions and Genes | Putrescine (N) |
|---|---|
| remove | |
| Aspartate kinase: L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4) | |
| b0002 (thrA) | -4.6 |
| b3940 (metL) | -1.0 |
| b4024 (lysC) | +1.3 |
| Aspartate-semialdehyde dehydrogenase (in reverse): L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11) | |
| b2319 (usg) | -0.3 |
| b3433 (asd) | N.D. |
| L-aspartate 4-semialdehyde + putrescine + NADPH + H+→carboxyspermidine + NADP+ + H2O (EC 1.5.1.43) | |
| No genes | |
| carboxyspermidine + H+→spermidine + CO2 (EC 4.1.1.96) | |
| No genes | |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information