MetaCyc Pathway: L-lysine degradation X in Escherichia coli BW25113

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Reactions and Genes Putrescine (N)
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Lysine decarboxylase:
L-lysine + H+→cadaverine + CO2 (EC 4.1.1.18)
b0186 (ldcC) -0.1
b4131 (cadA) -0.1
Putrescine aminotransferase:
cadaverine + 2-oxoglutarate→5-aminopentanal + L-glutamate (EC 2.6.1.82)
b3073 (ygjG) -1.4
Aminobutyraldehyde dehydrogenase:
5-aminopentanal + NAD+ + H2O→5-aminopentanoate + NADH + 2 H+ (EC 1.2.1.19)
b1444 (ydcW) -0.6
5-aminovalerate transaminase:
5-aminopentanoate + 2-oxoglutarate→glutarate semialdehyde + L-glutamate (EC 2.6.1.48)
b1302 (puuE) -0.9
b2662 (gabT) -0.6
Glutarate-semialdehyde dehydrogenase:
glutarate semialdehyde + NADP+ + H2O→glutarate + NADPH + 2 H+ (EC 1.2.1.20)
b1525 (b1525) -0.6
b2661 (gabD) +0.4
Succinate--hydroxymethylglutarate CoA-transferase:
glutarate + succinyl-CoA→glutaryl-CoA + succinate (EC 2.8.3.13)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information