MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Escherichia coli BW25113
Reactions and Genes | Gly-Glu (N) |
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Aspartate transaminase (in reverse): oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1) | |
b0928 (aspC) | -2.4 |
b4340 (yjiR) | -0.2 |
Aspartate ammonia-lyase (in reverse): fumarate + ammonium→L-aspartate (EC 4.3.1.1) | |
b4139 (aspA) | -0.1 |
Aspartate--ammonia ligase: L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H+ (EC 6.3.1.1) | |
b0674 (asnB) | -3.6 |
b3744 (asnA) | +0.1 |
Asparaginase: L-asparagine + H2O→L-aspartate + ammonium (EC 3.5.1.1; 3.5.1.38; 3.5.5.4) | |
b1767 (ansA) | +0.2 |
b2957 (ansB) | -0.0 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information