MetaCyc Pathway: L-tyrosine degradation I in Escherichia coli BW25113
| Reactions and Genes | D-Alanine (N) |
|---|---|
| remove | |
| Aspartate transaminase: L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57) | |
| b0928 (aspC) | -3.0 |
| b2021 (hisC) | -5.5 |
| b4054 (tyrB) | -1.1 |
| b4340 (yjiR) | +0.1 |
| 4-hydroxyphenylpyruvate dioxygenase: 3-(4-hydroxyphenyl)pyruvate + dioxygen→homogentisate + CO2 (EC 1.13.11.27) | |
| No genes | |
| Homogentisate 1,2-dioxygenase: homogentisate + dioxygen→4-maleyl-acetoacetate + H+ (EC 1.13.11.5) | |
| No genes | |
| Maleylacetoacetate isomerase: 4-maleyl-acetoacetate→4-fumaryl-acetoacetate (EC 5.2.1.2) | |
| No genes | |
| Fumarylacetoacetase: 4-fumaryl-acetoacetate + H2O→acetoacetate + fumarate + H+ (EC 3.7.1.2) | |
| No genes | |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information