MetaCyc Pathway: superpathway of anaerobic sucrose degradation in Serratia liquefaciens MT49

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Reactions and Genes Cobalt chloride 60 uM, anaerobic
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Sucrose synthase (in reverse):
sucrose + H+ + UDP→β-D-fructofuranose + UDP-α-D-glucose (EC 2.4.1.13)
No genes
Fructokinase:
β-D-fructofuranose + ATP→β-D-fructofuranose 6-phosphate + ADP + H+ (EC 2.7.1.4)
IAI46_04755 +0.1
IAI46_21675 +0.3
UTP-monosaccharide-1-phosphate uridylyltransferase (in reverse):
UDP-α-D-glucose + diphosphate→α-D-glucopyranose 1-phosphate + H+ + UTP (EC 2.7.7.64; 2.7.7.9)
IAI46_08000 -0.1
IAI46_08005 -0.2
IAI46_08120 -0.1
IAI46_14245 -0.2
6-phosphofructokinase:
β-D-fructofuranose 6-phosphate + ATP→β-D-fructofuranose 1,6-bisphosphate + ADP + H+ (EC 2.7.1.11)
IAI46_11575 -0.1
IAI46_24645 -2.2
Phosphoglucomutase:
α-D-glucopyranose 1-phosphate→D-glucopyranose 6-phosphate (EC 5.4.2.2)
IAI46_01905 N.D.
IAI46_06145 -0.4
Fructose-bisphosphate aldolase:
β-D-fructofuranose 1,6-bisphosphate→glycerone phosphate + D-glyceraldehyde 3-phosphate (EC 4.1.2.13)
IAI46_04740 -0.0
IAI46_10085 -0.1
IAI46_19050 +0.1
IAI46_21005 N.D.
Fructose-bisphosphatase:
β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
IAI46_01795 +0.0
IAI46_06500 -0.1
IAI46_07775 +0.2
IAI46_24605 -0.0
Glucose-6-phosphate isomerase:
α-D-glucose 6-phosphate→β-D-fructofuranose 6-phosphate (EC 5.3.1.9)
IAI46_21990 -0.1
IAI46_21995 -0.1
IAI46_23090 -2.7
Triose-phosphate isomerase (in reverse):
glycerone phosphate→D-glyceraldehyde 3-phosphate (EC 5.3.1.1)
IAI46_23990 -0.0
IAI46_24635 N.D.
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating):
D-glyceraldehyde 3-phosphate + NAD+ + phosphate→3-phospho-D-glyceroyl phosphate + NADH + H+ (EC 1.2.1.12)
IAI46_14355 N.D.
IAI46_16675 +0.2
Phosphoglycerate kinase (in reverse):
3-phospho-D-glyceroyl phosphate + ADP→3-phospho-D-glycerate + ATP (EC 2.7.2.3)
IAI46_21010 N.D.
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.12)
IAI46_03000 +0.2
IAI46_06410 N.D.
IAI46_24710 -0.2
3-phospho-D-glycerate→2-phospho-D-glycerate (EC 5.4.2.11)
IAI46_06410 N.D.
Phosphopyruvate hydratase:
2-phospho-D-glycerate→phosphoenolpyruvate + H2O (EC 4.2.1.11)
IAI46_03615 N.D.
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
IAI46_11185 +0.1
IAI46_14585 +0.1
L-lactate dehydrogenase (in reverse):
pyruvate + NADH + H+→(S)-lactate + NAD+ (EC 1.1.1.27)
No genes
Pyruvate, water dikinase:
pyruvate + ATP + H2O→phosphoenolpyruvate + AMP + 2 H+ + phosphate (EC 2.7.9.2)
IAI46_11115 -0.1
Pyruvate decarboxylase:
pyruvate + H+→acetaldehyde + CO2 (EC 4.1.1.1)
IAI46_04520 +0.0
IAI46_18240 +0.3
Alcohol dehydrogenase (in reverse):
acetaldehyde + NADH + H+→ethanol + NAD+ (EC 1.1.1.1)
IAI46_02655 -0.1
IAI46_07885 +0.1
IAI46_12310 -0.5
IAI46_14220 -1.8
IAI46_19495 -0.3
IAI46_21740 +0.0
IAI46_22730 -0.0
IAI46_22910 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information