MetaCyc Pathway: felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis in Escherichia coli BW25113

Reactions and Genes	D-Serine (N)
	remove
3-(glutathion-S-yl)-(3-methyl)butanol + H₂O→S-(3-methylbutan-3-yl)-L-cysteinylglycine + L-glutamate (EC 3.4.19.13)
No genes
S-(3-methylbutan-3-yl)-L-cysteinylglycine + H₂O→felinine + glycine (EC 3.4.13.23)
No genes
Cysteine-S-conjugate beta-lyase: felinine→2-aminoprop-2-enoate + 3-methyl-3-sulfanylbutan-1-ol (EC 4.4.1.13)
No genes
Tryptophanase: 2-aminoprop-2-enoate→2-iminopropanoate (spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
b1814 (sdaA)	-0.6
b1919 (yedO)	-0.3
b2366 (dsdA)	-3.4
b2797 (sdaB)	-0.1
b3708 (tnaA)	-0.0
b4471 (tdcG)	+0.1
2-iminopropanoate + H₂O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
b1814 (sdaA)	-0.6
b1919 (yedO)	-0.3
b2366 (dsdA)	-3.4
b2797 (sdaB)	-0.1
b3113 (yhaR)	+0.3
b3708 (tnaA)	-0.0
b4243 (yjgF)	-0.7
b4471 (tdcG)	+0.1

Links:

Pathway details at MetaCyc
Fitness data for 8 genes
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All MetaCyc pathways for Escherichia coli BW25113

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information