MetaCyc Pathway: pyruvate fermentation to propanoate I in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

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Reactions and Genes LB_plus_SM_buffer with FelixO1_phage 0.5 MOI
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Methylmalonyl-CoA carboxytransferase:
(S)-methylmalonyl-CoA + pyruvate→oxaloacetate + propanoyl-CoA (EC 2.1.3.1)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
GFF2149 -1.3
GFF2556 +1.4
GFF3033 +0.3
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
GFF10 N.D.
GFF1477 +0.1
GFF1806 +0.9
GFF1807 +0.9
GFF3577 +0.2
GFF9 N.D.
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
GFF1996 +0.0
GFF1997 -0.5
GFF1998 -0.1
GFF1999 -0.0
propanoyl-CoA + succinate→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
No genes
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information