| Reactions and Genes | L-Histidine (C) |
|---|
| remove |
Mandelate racemase (in reverse):
(R)-mandelate→(S)-mandelate (EC 5.1.2.2) |
| ABID97_RS09975 | +0.0 |
| ABID97_RS11525 | -1.0 |
(S)-mandelate dehydrogenase:
(S)-mandelate + an oxidized electron carrier→phenylglyoxylate + a reduced two electron carrier (EC 1.1.99.31) |
| ABID97_RS11550 | N.D. |
| ABID97_RS24575 | +0.2 |
Benzoylformate decarboxylase:
phenylglyoxylate + H+→benzaldehyde + CO2 (EC 4.1.1.7) |
| ABID97_RS13225 | -0.2 |
| ABID97_RS24605 | -1.1 |
Benzaldehyde dehydrogenase (NAD(+)):
benzaldehyde + NAD+ + H2O→benzoate + NADH + 2 H+ (EC 1.2.1.28) |
| No genes |
Benzaldehyde dehydrogenase (NADP(+)):
benzaldehyde + NADP+ + H2O→benzoate + NADPH + 2 H+ (EC 1.2.1.7) |
| No genes |
Benzoate 1,2-dioxygenase:
benzoate + NADH + dioxygen + H+→3,5-cyclohexadiene-1,2-diol-1-carboxylate + NAD+ (EC 1.14.12.10) |
| ABID97_RS16055 | -0.5 |
| ABID97_RS18640 | N.D. |
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase:
3,5-cyclohexadiene-1,2-diol-1-carboxylate + NAD+→catechol + CO2 + NADH (EC 1.3.1.25) |
| No genes |
Catechol 1,2-dioxygenase:
catechol + dioxygen→cis,cis-muconate + 2 H+ (EC 1.13.11.1) |
| ABID97_RS13200 | N.D. |
| ABID97_RS28895 | -0.3 |
| ABID97_RS29155 | +0.4 |
Catechol 2,3-dioxygenase:
catechol + dioxygen→(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H+ (EC 1.13.11.2) |
| ABID97_RS26345 | -0.4 |
| ABID97_RS27995 | +0.4 |
2-hydroxymuconate-semialdehyde hydrolase:
(2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O→(2Z)-2-hydroxypenta-2,4-dienoate + formate + H+ (EC 3.7.1.9) |
| ABID97_RS08810 | -0.5 |
Muconate cycloisomerase (in reverse):
cis,cis-muconate + H+→(+)-muconolactone (EC 5.5.1.1) |
| No genes |
2-oxopent-4-enoate hydratase (in reverse):
(2Z)-2-hydroxypenta-2,4-dienoate + H2O→(S)-4-hydroxy-2-oxopentanoate (EC 4.2.1.80) |
| ABID97_RS15830 | +0.1 |
| ABID97_RS27940 | N.D. |
Muconolactone Delta-isomerase:
(+)-muconolactone→(4,5-dihydro-5-oxofuran-2-yl)-acetate (EC 5.3.3.4) |
| ABID97_RS13085 | -0.0 |
3-oxoadipate enol-lactonase:
(4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O→3-oxoadipate + H+ (EC 3.1.1.24) |
| ABID97_RS11395 | -0.2 |
| ABID97_RS19695 | +0.1 |
| ABID97_RS23830 | -0.3 |
| ABID97_RS25555 | N.D. |
| ABID97_RS27270 | N.D. |
| ABID97_RS29170 | +0.1 |
4-hydroxy-2-oxovalerate aldolase:
(S)-4-hydroxy-2-oxopentanoate→acetaldehyde + pyruvate (EC 4.1.3.39) |
| ABID97_RS27920 | -0.0 |
3-oxoadipate CoA-transferase:
3-oxoadipate + succinyl-CoA→3-oxoadipoyl-CoA + succinate (EC 2.8.3.6) |
| ABID97_RS13250 | +0.0 |
| ABID97_RS13255 | +0.4 |
| ABID97_RS24195 | +0.3 |
| ABID97_RS24200 | +0.4 |
Acetaldehyde dehydrogenase (acetylating):
acetaldehyde + coenzyme A + NAD+→acetyl-CoA + NADH + H+ (EC 1.2.1.10) |
| ABID97_RS27925 | +0.3 |
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→acetyl-CoA + succinyl-CoA (EC 2.3.1.174) |
| ABID97_RS24190 | +0.1 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information