MetaCyc Pathway: 4-hydroxybenzoate biosynthesis III (plants) in Variovorax sp. OAS795

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Reactions and Genes Tween 20 (C)
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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate (EC 6.2.1.12)
ABID97_RS28960 +0.3
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
ABID97_RS24015 +0.5
3-hydroxyacyl-CoA dehydrogenase:
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA + NAD+→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + NADH + H+ (EC 1.1.1.35)
ABID97_RS03030 -0.1
ABID97_RS05865 -1.4
ABID97_RS06010 -0.1
ABID97_RS08805 +0.1
ABID97_RS10560 -0.3
ABID97_RS15740 -0.8
ABID97_RS17005 -0.3
ABID97_RS18595 N.D.
Acetyl-CoA C-acyltransferase (in reverse):
3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
ABID97_RS04675 +0.0
ABID97_RS05875 N.D.
ABID97_RS06005 -0.1
ABID97_RS10975 -0.1
ABID97_RS11335 -0.1
ABID97_RS11380 +0.1
ABID97_RS12420 N.D.
ABID97_RS15750 +0.1
ABID97_RS18615 -0.3
ABID97_RS18775 +0.1
ABID97_RS20240 +0.0
ABID97_RS24190 +0.4
ABID97_RS25195 -0.4
ABID97_RS26575 N.D.
ABID97_RS27835 -0.0
ABID97_RS28230 +0.8
ABID97_RS28270 -0.1
ABID97_RS28430 +0.2
4-hydroxybenzoyl-CoA thioesterase:
4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+ (EC 3.1.2.23)
ABID97_RS08930 +0.5
ABID97_RS22155 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information