MetaCyc Pathway: superpathway of L-aspartate and L-asparagine biosynthesis in Escherichia coli BW25113
| Reactions and Genes | L-Asparagine (N) |
|---|---|
| remove | |
| Aspartate transaminase (in reverse): oxaloacetate + L-glutamate→L-aspartate + 2-oxoglutarate (EC 2.6.1.1) | |
| b0928 (aspC) | -0.4 |
| b4340 (yjiR) | +0.1 |
| Aspartate ammonia-lyase (in reverse): fumarate + ammonium→L-aspartate (EC 4.3.1.1) | |
| b4139 (aspA) | -0.2 |
| Aspartate--ammonia ligase: L-aspartate + ammonium + ATP→L-asparagine + AMP + diphosphate + H+ (EC 6.3.1.1) | |
| b0674 (asnB) | -0.1 |
| b3744 (asnA) | +0.0 |
| Asparaginase: L-asparagine + H2O→L-aspartate + ammonium (EC 3.5.1.1; 3.5.1.38; 3.5.5.4) | |
| b1767 (ansA) | -4.4 |
| b2957 (ansB) | -0.0 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information