MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Variovorax sp. OAS795

Reactions and Genes	D,L-Malic Acid (C)
2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
ABID97_RS01385	-0.1
ABID97_RS01390	-0.1
Succinate--CoA ligase (ADP-forming) (in reverse): succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
ABID97_RS02240	N.D.
ABID97_RS02245	N.D.
ABID97_RS24470	+0.1
ABID97_RS24475	+0.6
Succinate dehydrogenase (ubiquinone): succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
ABID97_RS08495	N.D.
Fumarate hydratase (in reverse): fumarate + H2O→(S)-malate (EC 4.2.1.2)
ABID97_RS17545	+1.2
ABID97_RS17550	-0.2
Malate dehydrogenase: (S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
ABID97_RS05795	-0.2
ABID97_RS08515	N.D.
ABID97_RS17295	+0.1
Aspartate transaminase (in reverse): oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
ABID97_RS04080	-0.2
ABID97_RS05635	-0.1
ABID97_RS06550	-0.0
ABID97_RS10885	-3.3
ABID97_RS13335	-0.1
ABID97_RS16605	-0.0
ABID97_RS17960	+0.2
ABID97_RS18035	+0.5
ABID97_RS20530	-0.2
ABID97_RS21960	-0.1
ABID97_RS24840	-0.1
ABID97_RS27360	+0.2
ABID97_RS27595	-0.1
ABID97_RS27655	-0.1

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information