MetaCyc Pathway: acridone alkaloid biosynthesis in Pontibacter actiniarum KMM 6156, DSM 19842

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Reactions and Genes m.b. Chloride 750 mM
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Anthranilate synthase:
chorismate + L-glutamine→anthranilate + L-glutamate + H+ + pyruvate (EC 4.1.3.27)
CA264_05055 -1.2
CA264_05060 -1.1
CA264_15260 -0.6
Anthranilate N-methyltransferase:
anthranilate + S-adenosyl-L-methionine→N-methylanthranilate + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.111)
No genes
N-methylanthranilate + ATP + coenzyme A→N-methylanthraniloyl-CoA + AMP + diphosphate
No genes
Acridone synthase:
N-methylanthraniloyl-CoA + 3 malonyl-CoA→1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 coenzyme A (EC 2.3.1.159)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information