MetaCyc Pathway: superpathway of anaerobic energy metabolism (invertebrates) in Variovorax sp. OAS795

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Reactions and Genes propionate (C)
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Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + GDP→oxaloacetate + GTP (EC 4.1.1.32)
ABID97_RS03370 +0.0
Pyruvate kinase (in reverse):
phosphoenolpyruvate + ADP + H+→pyruvate + ATP (EC 2.7.1.40)
ABID97_RS01755 -0.9
ABID97_RS24455 +0.1
ABID97_RS27675 -0.0
Phosphoenolpyruvate carboxykinase (GTP) (in reverse):
phosphoenolpyruvate + CO2 + IDP→oxaloacetate + ITP (EC 4.1.1.32)
ABID97_RS03370 +0.0
Alanine transaminase (in reverse):
pyruvate + L-glutamate→2-oxoglutarate + L-alanine (EC 2.6.1.2)
ABID97_RS10885 -0.5
Alanine racemase:
L-alanine→D-alanine (EC 5.1.1.1; 5.1.1.10)
ABID97_RS03685 N.D.
ABID97_RS13370 +1.0
Aspartate transaminase:
2-oxoglutarate + L-aspartate→L-glutamate + oxaloacetate (EC 2.6.1.1)
ABID97_RS04080 +0.2
ABID97_RS05635 +0.2
ABID97_RS06550 -0.1
ABID97_RS10885 -0.5
ABID97_RS13335 -0.0
ABID97_RS16605 -0.0
ABID97_RS17960 -0.3
ABID97_RS18035 +0.3
ABID97_RS20530 -0.2
ABID97_RS21960 -0.4
ABID97_RS24840 +0.2
ABID97_RS27360 +0.1
ABID97_RS27595 -0.1
ABID97_RS27655 -0.7
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
ABID97_RS05795 -0.4
ABID97_RS08515 N.D.
ABID97_RS17295 +0.0
Malate dehydrogenase (oxaloacetate-decarboxylating):
(S)-malate + NAD+→pyruvate + CO2 + NADH (EC 1.1.1.38)
No genes
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
ABID97_RS17545 -0.2
ABID97_RS17550 -0.2
pyruvate + coenzyme A + NAD+→CO2 + acetyl-CoA + NADH (EC 1.2.1.104)
ABID97_RS01385 +0.2
ABID97_RS01390 -0.1
ABID97_RS14105 -0.6
ABID97_RS26535 +0.4
Succinate dehydrogenase (ubiquinone) (in reverse):
fumarate[in] + a rhodoquinol→succinate[in] + a rhodoquinone (EC 1.3.5.1)
No genes
acetyl-CoA + succinate→acetate + succinyl-CoA (EC 2.8.3.18)
No genes
succinate + propanoyl-CoA→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
ABID97_RS13930 +8.2
Succinate--CoA ligase (ADP-forming) (in reverse):
succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
ABID97_RS02240 N.D.
ABID97_RS02245 N.D.
ABID97_RS24470 -0.3
ABID97_RS24475 +0.2
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
ABID97_RS13960 N.D.
Propionyl-CoA carboxylase (in reverse):
(S)-methylmalonyl-CoA + ADP + H+ + phosphate→propanoyl-CoA + ATP + hydrogen carbonate (EC 6.4.1.3)
ABID97_RS08420 N.D.
ABID97_RS13945 -4.4
ABID97_RS13950 -3.5
ABID97_RS17835 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information