MetaCyc Pathway: L-serine degradation in Escherichia coli BW25113

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Reactions and Genes D-Galacturonic Acid (C) MOPS
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L-serine ammonia-lyase:
L-serine→2-aminoprop-2-enoate + H2O
(EC 4.3.1.17)
b1814 (sdaA) -1.2
b2797 (sdaB) -0.6
b4471 (tdcG) -0.0
Tryptophanase:
2-aminoprop-2-enoate→2-iminopropanoate
(spontaneous) (EC 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
b1814 (sdaA) -1.2
b1919 (yedO) -0.2
b2366 (dsdA) -0.3
b2797 (sdaB) -0.6
b3708 (tnaA) -0.1
b4471 (tdcG) -0.0
2-iminopropanoate + H2O→pyruvate + ammonium (spontaneous) (EC 3.5.99.10; 4.1.99.1; 4.1.99.2; 4.3.1.13; 4.3.1.17; 4.3.1.18; 4.3.3.8; 4.4.1.1; 4.4.1.13; 4.4.1.15; 4.4.1.25; 4.4.1.28; 4.4.1.35; 4.5.1.2)
b1814 (sdaA) -1.2
b1919 (yedO) -0.2
b2366 (dsdA) -0.3
b2797 (sdaB) -0.6
b3113 (yhaR) +0.2
b3708 (tnaA) -0.1
b4243 (yjgF) -1.9
b4471 (tdcG) -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information