MetaCyc Pathway: superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis in Variovorax sp. OAS795

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Reactions and Genes D-Glucuronic Acid (C)
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Phosphoglucomutase (in reverse):
D-glucopyranose 6-phosphate→α-D-glucopyranose 1-phosphate (EC 5.4.2.2)
ABID97_RS15660 +0.4
ABID97_RS17035 N.D.
ABID97_RS21385 +0.6
UTP-monosaccharide-1-phosphate uridylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + UTP→UDP-α-D-glucose + diphosphate (EC 2.7.7.64; 2.7.7.9)
ABID97_RS07895 N.D.
UDP-glucose 4-epimerase:
UDP-α-D-glucose→UDP-α-D-galactose (EC 5.1.3.2)
ABID97_RS05700 -2.0
ABID97_RS05765 -1.0
ABID97_RS10350 -5.3
ABID97_RS11875 -0.0
ABID97_RS11880 +0.2
ABID97_RS13410 +0.2
ABID97_RS24220 -0.0
UDP-glucose 6-dehydrogenase:
UDP-α-D-glucose + 2 NAD+ + H2O→UDP-α-D-glucuronate + 2 NADH + 3 H+ (EC 1.1.1.22)
ABID97_RS02195 +1.3
ABID97_RS11855 -0.0
UDP-galactopyranose mutase:
UDP-α-D-galactose→UDP-α-D-galactofuranose (EC 5.4.99.9)
No genes
UDP-glucuronate 4-epimerase:
UDP-α-D-glucuronate→UDP-α-D-galacturonate (EC 5.1.3.6)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information