MetaCyc Pathway: 3-hydroxy-4-methyl-anthranilate biosynthesis II in Pontibacter actiniarum KMM 6156, DSM 19842

Add experiment(s):


Reactions and Genes m.b. Thallium(I) acetate 0.001 mg/ml
remove
Tryptophan 2,3-dioxygenase:
L-tryptophan + dioxygen→N-formyl-L-kynurenine (EC 1.13.11.11; 1.13.11.52)
CA264_05650 +1.4
Arylformamidase:
N-formyl-L-kynurenine + H2O→L-kynurenine + formate + H+ (EC 3.5.1.9)
CA264_16775 +0.7
Kynurenine 3-monooxygenase:
L-kynurenine + NADPH + dioxygen + H+→3-hydroxy-L-kynurenine + NADP+ + H2O (EC 1.14.13.9)
CA264_18040 +1.5
3-hydroxy-L-kynurenine + S-adenosyl-L-methionine→3-hydroxy-4-methyl-L-kynurenine + S-adenosyl-L-homocysteine + H+ (EC 2.1.1.M26)
No genes
Kynureninase:
3-hydroxy-4-methyl-L-kynurenine + H2O→3-hydroxy-4-methylanthranilate + L-alanine + H+ (EC 3.7.1.3)
CA264_18015 +0.9

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information