MetaCyc Pathway: L-tyrosine biosynthesis I in Escherichia coli BW25113

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Reactions and Genes L-Malic (C)
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Chorismate mutase:
chorismate→prephenate
(EC 5.4.99.5)
b2599 (pheA) -2.7
b2600 (tyrA) -4.1
Prephenate dehydrogenase:
prephenate + NAD+→3-(4-hydroxyphenyl)pyruvate + CO2 + NADH
(EC 1.3.1.12)
b2600 (tyrA) -4.1
Aspartate transaminase (in reverse):
3-(4-hydroxyphenyl)pyruvate + L-glutamate→L-tyrosine + 2-oxoglutarate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
b0928 (aspC) -1.1
b2021 (hisC) -4.5
b4054 (tyrB) -1.4
b4340 (yjiR) +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information