MetaCyc Pathway: superpathway of L-alanine biosynthesis in Escherichia coli BW25113
| Reactions and Genes | L-Malic (C) |
|---|---|
| remove | |
| Alanine transaminase (in reverse): pyruvate + L-glutamate→L-alanine + 2-oxoglutarate (EC 2.6.1.2) | |
| b2290 (yfbQ) | +0.4 |
| b2379 (yfdZ) | +0.0 |
| Branched-chain-amino-acid transaminase (in reverse): 3-methyl-2-oxobutanoate + L-glutamate→L-valine + 2-oxoglutarate (EC 2.6.1.42) | |
| b3770 (ilvE) | -4.2 |
| Cysteine desulfurase: L-cysteine + an unsulfurated [sulfur carrier]→L-alanine + a sulfurated [sulfur carrier] (EC 2.8.1.7) | |
| b1680 (sufS) | -0.1 |
| b2810 (csdA) | +1.1 |
| b2811 (ygdK) | +0.8 |
| b2530 (iscS) | N.D. |
| Valine--pyruvate transaminase: L-valine + pyruvate→3-methyl-2-oxobutanoate + L-alanine (EC 2.6.1.66) | |
| b2290 (yfbQ) | +0.4 |
| b3572 (avtA) | -1.2 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information