MetaCyc Pathway: 2-allylmalonyl-CoA biosynthesis in Variovorax sp. OAS795

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Reactions and Genes D-Arabinose (C)
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propanoyl-CoA + TcsB polyketide synthase→propanoyl-[TcsB polyketide synthase] + coenzyme A
No genes
malonyl-CoA + TcsA polyketide synthase→malonyl-[TcsA polyketide synthase] + coenzyme A
No genes
malonyl-[TcsA polyketide synthase] + propanoyl-[TcsB polyketide synthase] + H+→3-oxopentanoyl-[TcsA polyketide synthase] + CO2 + TcsB polyketide synthase
No genes
3-oxoacyl-[acyl-carrier-protein] reductase (in reverse):
3-oxopentanoyl-[TcsA polyketide synthase] + NADPH + H+→(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase] + NADP+ (EC 1.1.1.100)
ABID97_RS01400 -0.1
ABID97_RS03055 -0.2
ABID97_RS03260 N.D.
ABID97_RS04295 -0.1
ABID97_RS05575 -0.2
ABID97_RS05830 +2.4
ABID97_RS08310 N.D.
ABID97_RS08870 N.D.
ABID97_RS10320 +0.0
ABID97_RS11250 +0.1
ABID97_RS11585 N.D.
ABID97_RS11630 -0.3
ABID97_RS14425 +0.1
ABID97_RS14760 +0.6
ABID97_RS15765 +0.0
ABID97_RS16045 N.D.
ABID97_RS16765 +0.2
ABID97_RS17320 -0.0
ABID97_RS18630 +0.4
ABID97_RS18660 +0.2
ABID97_RS18980 +0.3
ABID97_RS18985 +0.1
ABID97_RS18990 -0.2
ABID97_RS22670 N.D.
ABID97_RS24025 +0.3
ABID97_RS25995 N.D.
ABID97_RS26005 N.D.
ABID97_RS26430 N.D.
ABID97_RS27295 N.D.
ABID97_RS28245 +1.2
ABID97_RS28425 +0.0
ABID97_RS28765 N.D.
ABID97_RS29505 -0.6
3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase:
(3R)-3-hydroxypentanoyl-[TcsA polyketide synthase]→(2E)-pent-2-enoyl-[TcsA polyketide synthase] + H2O (EC 4.2.1.59)
ABID97_RS17115 N.D.
(2E)-pent-2-enoyl-[TcsA polyketide synthase] + CO2 + NADPH→2-carboxypentanoyl-[TcsA polyketide synthase] + NADP+
No genes
2-carboxypentanoyl-[TcsA polyketide synthase] + FAD + H+→2-allylmalonyl-[TcsA polyketide synthase] + FADH2
No genes
2-allylmalonyl-[TcsA polyketide synthase] + coenzyme A→2-allylmalonyl-CoA + TcsA polyketide synthase
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information