MetaCyc Pathway: D-glucarate degradation I in Escherichia coli BW25113

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Reactions and Genes Glycolic Acid (C)
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Glucarate dehydratase:
D-glucarate→5-dehydro-4-deoxy-D-glucarate + H2O (EC 4.2.1.40)
b2787 (gudD) +0.4
b2788 (gudX) +0.1
2-dehydro-3-deoxyglucarate aldolase:
5-dehydro-4-deoxy-D-glucarate→(2R)-tartronate semialdehyde + pyruvate (EC 4.1.2.20)
b3126 (garL) -1.0
2-hydroxy-3-oxopropionate reductase (in reverse):
(2R)-tartronate semialdehyde + NAD(P)H + H+→D-glycerate + NAD(P)+ (EC 1.1.1.60)
b0509 (glxR) -1.4
b3125 (garR) -1.3
D-glycerate + ATP→2-phospho-D-glycerate + ADP + H+ (EC 2.7.1.165)
b0514 (glxK) +0.1
b3124 (garK) -4.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information