MetaCyc Pathway: gluconeogenesis III in Escherichia coli BW25113

Reactions and Genes	succinate (C)
Pyruvate carboxylase: pyruvate + ATP + hydrogen carbonate→oxaloacetate + ADP + H+ + phosphate (EC 6.4.1.1)
No genes
Malate dehydrogenase: (S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
b0801 (ybiC)	+0.3
b1479 (sfcA)	-2.8
b3236 (mdh)	-1.4
Phosphoenolpyruvate carboxykinase (GTP): oxaloacetate + GTP→phosphoenolpyruvate + CO2 + GDP (EC 4.1.1.32)
No genes
Phosphopyruvate hydratase (in reverse): phosphoenolpyruvate + H2O→2-phospho-D-glycerate (EC 4.2.1.11)
b2779 (eno)	N.D.
2-phospho-D-glycerate→3-phospho-D-glycerate (EC 5.4.2.11)
b0755 (gpmA)	-0.1
Phosphoglycerate kinase: 3-phospho-D-glycerate + ATP→3-phospho-D-glyceroyl phosphate + ADP (EC 2.7.2.3)
b2926 (pgk)	N.D.
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (in reverse): 3-phospho-D-glyceroyl phosphate + NADH + H+→D-glyceraldehyde 3-phosphate + NAD+ + phosphate (EC 1.2.1.12)
b1779 (gapA)	N.D.
Triose-phosphate isomerase: D-glyceraldehyde 3-phosphate→glycerone phosphate (EC 5.3.1.1)
b3919 (tpiA)	N.D.
Fructose-bisphosphate aldolase (in reverse): glycerone phosphate + D-glyceraldehyde 3-phosphate→β-D-fructofuranose 1,6-bisphosphate (EC 4.1.2.13)
b2097 (b2097)	+0.1
b2925 (fbaA)	N.D.
Fructose-bisphosphatase: β-D-fructofuranose 1,6-bisphosphate + H2O→β-D-fructofuranose 6-phosphate + phosphate (EC 3.1.3.11)
b0383 (phoA)	+0.3
b0766 (ybhA)	-0.1
b2930 (yggF)	+0.1
b3925 (glpX)	+0.1
b4232 (fbp)	-5.4
Glucose-6-phosphate isomerase (in reverse): β-D-fructofuranose 6-phosphate→α-D-glucose 6-phosphate (EC 5.3.1.9)
b2843 (kduI)	+0.1
b4025 (pgi)	+1.4
Sugar-terminal-phosphatase: D-glucopyranose 6-phosphate + H2O→D-glucopyranose + phosphate (EC 3.1.3.58; 3.1.3.9)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information