MetaCyc Pathway: L-tyrosine degradation IV (to 4-methylphenol) in Escherichia coli BW25113

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Reactions and Genes succinate (C)
remove
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
b0928 (aspC) -0.5
b2021 (hisC) -5.1
b4054 (tyrB) -1.1
b4340 (yjiR) +0.1
4-hydroxyphenylpyruvate oxidase:
2 3-(4-hydroxyphenyl)pyruvate + dioxygen→2 (4-hydroxyphenyl)acetate + 2 CO2
(EC 1.2.3.13)
No genes
4-hydroxyphenylacetate decarboxylase:
(4-hydroxyphenyl)acetate + H+→4-methylphenol + CO2
(EC 4.1.1.83)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information