MetaCyc Pathway: L-glutamate degradation VIII (to propanoate) in Escherichia coli BW25113

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Reactions and Genes succinate (C)
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Methylaspartate mutase (in reverse):
L-glutamate→(2S, 3S)-3-methylaspartate (EC 5.4.99.1)
No genes
Methylaspartate ammonia-lyase:
(2S, 3S)-3-methylaspartate→mesaconate + ammonium (EC 4.3.1.2)
No genes
(S)-2-methylmalate dehydratase (in reverse):
mesaconate + H2O→(S)-citramalate (EC 4.2.1.34)
No genes
Citramalate lyase:
(S)-citramalate→pyruvate + acetate (EC 4.1.3.22)
No genes
Methylmalonyl-CoA carboxytransferase:
(S)-methylmalonyl-CoA + pyruvate→oxaloacetate + propanoyl-CoA (EC 2.1.3.1)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
b0801 (ybiC) +0.3
b1479 (sfcA) -2.8
b3236 (mdh) -1.4
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
b1611 (fumC) +0.4
b1612 (fumA) -1.7
b1675 (ydhZ) -0.4
b2929 (yggD) -0.0
b4122 (fumB) -0.0
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
b4151 (frdD) +0.1
b4152 (frdC) +0.3
b4153 (frdB) +0.1
b4154 (frdA) +0.4
propanoyl-CoA + succinate→succinyl-CoA + propanoate (EC 2.8.3.27)
b2920 (ygfH) +0.2
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
b2917 (yliK) +0.0
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information