MetaCyc Pathway: 5-(methoxycarbonylmethoxy)uridine biosynthesis in Escherichia coli BW25113

Reactions and Genes	pyruvate (C)
	remove
prephenate + S-adenosyl-L-methionine→S-adenosyl-S-carboxymethyl-L-homocysteine + 3-phenyl-2-oxopropanoate + H₂O
b1870 (yecO)	N.D.
S-adenosyl-S-carboxymethyl-L-homocysteine + a 5-hydroxyuridine³⁴ in tRNA→a 5-(carboxymethoxy)uridine³⁴ in tRNA + S-adenosyl-L-homocysteine + H⁺
b1871 (yecP)	-1.6
a 5-(carboxymethoxy)uridine³⁴ in tRNA + S-adenosyl-L-methionine→a 5-(methoxycarbonylmethoxy)uridine³⁴ in tRNA + S-adenosyl-L-homocysteine (EC 2.1.1.M28)
b0921 (smtA)	-0.2

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Pathway details at MetaCyc
Fitness data for 3 genes
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All MetaCyc pathways for Escherichia coli BW25113

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information