MetaCyc Pathway: L-arginine biosynthesis II (acetyl cycle) in Pseudomonas fluorescens GW456-L13

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Reactions and Genes Putrescine (C)
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Glutamate--ammonia ligase:
L-glutamate + ammonium + ATP→L-glutamine + ADP + H+ + phosphate (EC 6.3.1.2)
PfGW456L13_1993 +0.4
PfGW456L13_2714 +0.3
PfGW456L13_3221 +0.2
PfGW456L13_342 N.D.
PfGW456L13_3804 +0.5
PfGW456L13_4498 +0.2
PfGW456L13_925 -2.9
PfGW456L13_926 -4.2
Amino-acid N-acetyltransferase:
L-glutamate + acetyl-CoA→N-acetyl-L-glutamate + coenzyme A + H+ (EC 2.3.1.1)
PfGW456L13_1834 -0.1
PfGW456L13_731 -0.6
PfGW456L13_913 -4.2
Acetylglutamate kinase:
N-acetyl-L-glutamate + ATP→N-acetylglutamyl-phosphate + ADP (EC 2.7.2.8)
PfGW456L13_793 -3.3
Carbamoyl-phosphate synthase (glutamine-hydrolyzing):
L-glutamine + 2 ATP + hydrogen carbonate + H2O→L-glutamate + carbamoyl phosphate + 2 ADP + 2 H+ + phosphate (EC 6.3.5.5)
PfGW456L13_5099 N.D.
PfGW456L13_5100 N.D.
N-acetyl-gamma-glutamyl-phosphate reductase (in reverse):
N-acetylglutamyl-phosphate + NADPH + H+→N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.38)
PfGW456L13_1233 -3.4
Ornithine carbamoyltransferase:
carbamoyl phosphate + L-ornithine→L-citrulline + H+ + phosphate (EC 2.1.3.3)
PfGW456L13_1739 -4.1
PfGW456L13_1873 -0.1
Acetylornithine transaminase (in reverse):
N-acetyl-L-glutamate 5-semialdehyde + L-glutamate→N-acetyl-L-ornithine + 2-oxoglutarate (EC 2.6.1.11)
PfGW456L13_1158 +0.1
PfGW456L13_1971 +0.1
PfGW456L13_4910 -0.2
Argininosuccinate synthase:
L-citrulline + ATP + L-aspartate→L-arginino-succinate + AMP + diphosphate + H+ (EC 6.3.4.5)
PfGW456L13_1749 -3.2
Argininosuccinate lyase:
L-arginino-succinate→L-arginine + fumarate (EC 4.3.2.1)
PfGW456L13_854 -3.0
Glutamate N-acetyltransferase:
L-glutamate + N-acetyl-L-ornithine→N-acetyl-L-glutamate + L-ornithine (EC 2.3.1.35)
PfGW456L13_1834 -0.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information