MetaCyc Pathway: pyruvate fermentation to propanoate I in Pontibacter actiniarum KMM 6156, DSM 19842

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Reactions and Genes m.b. Thallium(I) acetate 0.001 mg/ml
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Methylmalonyl-CoA carboxytransferase:
(S)-methylmalonyl-CoA + pyruvate→oxaloacetate + propanoyl-CoA (EC 2.1.3.1)
No genes
Malate dehydrogenase (in reverse):
oxaloacetate + NADH + H+→(S)-malate + NAD+ (EC 1.1.1.37; 1.1.1.38)
CA264_13275 N.D.
CA264_19515 N.D.
Fumarate hydratase:
(S)-malate→fumarate + H2O (EC 4.2.1.2)
CA264_17145 N.D.
Succinate dehydrogenase (ubiquinone):
fumarate[in] + a menaquinol→succinate[in] + a menaquinone (EC 1.3.5.1)
No genes
propanoyl-CoA + succinate→succinyl-CoA + propanoate (EC 2.8.3.27)
No genes
Methylmalonyl-CoA mutase (in reverse):
succinyl-CoA→(R)-methylmalonyl-CoA (EC 5.4.99.2)
CA264_07155 +0.5
CA264_20690 +1.9
CA264_20695 +1.8
Methylmalonyl-CoA epimerase:
(R)-methylmalonyl-CoA→(S)-methylmalonyl-CoA (EC 5.1.99.1)
CA264_11050 +1.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information