MetaCyc Pathway: glycine degradation in Pseudomonas fluorescens GW456-L13

Reactions and Genes	L-Tryptophan (C)
glycine + NAD+ + a tetrahydrofolate→ammonium + a 5,10-methylenetetrahydrofolate + CO2 + NADH (EC 1.4.1.27)
PfGW456L13_1869	+0.3
PfGW456L13_4267	N.D.
PfGW456L13_698	+0.0
PfGW456L13_902	-1.6
Glycine hydroxymethyltransferase (in reverse): glycine + a 5,10-methylenetetrahydrofolate + H2O→L-serine + a tetrahydrofolate (EC 2.1.2.1)
PfGW456L13_1116	-0.4
PfGW456L13_1451	N.D.
PfGW456L13_1452	-0.2
PfGW456L13_2685	-0.2
L-serine ammonia-lyase: L-serine→ammonium + pyruvate (EC 4.3.1.17)
PfGW456L13_1089	+0.1
PfGW456L13_1867	+0.4
PfGW456L13_4954	+0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information