MetaCyc Pathway: L-ornithine biosynthesis I in Pseudomonas fluorescens GW456-L13

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Reactions and Genes L-Tryptophan (C)
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Amino-acid N-acetyltransferase:
L-glutamate + acetyl-CoA→N-acetyl-L-glutamate + coenzyme A + H+ (EC 2.3.1.1)
PfGW456L13_1834 +1.7
PfGW456L13_731 -0.2
PfGW456L13_913 -5.3
Acetylglutamate kinase:
N-acetyl-L-glutamate + ATP→N-acetylglutamyl-phosphate + ADP (EC 2.7.2.8)
PfGW456L13_793 -4.8
N-acetyl-gamma-glutamyl-phosphate reductase (in reverse):
N-acetylglutamyl-phosphate + NADPH + H+→N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.38)
PfGW456L13_1233 -4.6
Acetylornithine transaminase (in reverse):
N-acetyl-L-glutamate 5-semialdehyde + L-glutamate→N-acetyl-L-ornithine + 2-oxoglutarate (EC 2.6.1.11)
PfGW456L13_1158 +0.3
PfGW456L13_1971 +1.8
PfGW456L13_4910 -0.2
Acetylornithine deacetylase:
N-acetyl-L-ornithine + H2O→L-ornithine + acetate (EC 3.5.1.16)
PfGW456L13_912 +0.2

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information