MetaCyc Pathway: 3-phenylpropanoate degradation in Variovorax sp. OAS795

Reactions and Genes	4-Hydroxybenzoic Acid (C)
3-phenylpropanoate + ATP + coenzyme A→3-phenylpropanoyl-CoA + AMP + diphosphate
No genes
3-phenylpropanoyl-CoA + an oxidized electron carrier→(E)-cinnamoyl-CoA + a reduced two electron carrier
No genes
Enoyl-CoA hydratase (in reverse): (E)-cinnamoyl-CoA + H2O→(S)-3-hydroxy-3-phenylpropanoyl-CoA (EC 4.2.1.17)
ABID97_RS00815	+0.1
ABID97_RS01435	+0.1
ABID97_RS02880	+0.2
ABID97_RS03115	-0.3
ABID97_RS04670	+0.0
ABID97_RS05865	-1.6
ABID97_RS05900	+0.0
ABID97_RS05990	-0.1
ABID97_RS06010	+0.3
ABID97_RS07755	+0.2
ABID97_RS10620	N.D.
ABID97_RS14445	+0.3
ABID97_RS15740	-0.3
ABID97_RS17005	-0.5
ABID97_RS17010	+0.0
ABID97_RS17470	+0.2
ABID97_RS18490	-0.2
ABID97_RS18595	N.D.
ABID97_RS18600	+0.2
ABID97_RS18605	N.D.
ABID97_RS18635	-0.8
ABID97_RS19410	+0.6
ABID97_RS20990	+0.5
ABID97_RS22770	+0.0
ABID97_RS24015	+0.4
ABID97_RS24805	+1.5
ABID97_RS26735	N.D.
ABID97_RS27490	+0.1
ABID97_RS27535	+0.6
ABID97_RS27555	-0.2
ABID97_RS27620	N.D.
ABID97_RS28260	N.D.
ABID97_RS28410	N.D.
ABID97_RS29050	-0.3
3-hydroxyacyl-CoA dehydrogenase: (S)-3-hydroxy-3-phenylpropanoyl-CoA + NAD+→3-oxo-3-phenylpropanoyl-CoA + NADH + H+ (EC 1.1.1.35)
ABID97_RS03030	+0.2
ABID97_RS05865	-1.6
ABID97_RS06010	+0.3
ABID97_RS08805	-0.1
ABID97_RS10560	-0.0
ABID97_RS15740	-0.3
ABID97_RS17005	-0.5
ABID97_RS18595	N.D.
Acetyl-CoA C-acyltransferase (in reverse): 3-oxo-3-phenylpropanoyl-CoA + coenzyme A→benzoyl-CoA + acetyl-CoA (EC 2.3.1.16)
ABID97_RS04675	+0.2
ABID97_RS05875	N.D.
ABID97_RS06005	+0.4
ABID97_RS10975	+0.0
ABID97_RS11335	+0.8
ABID97_RS11380	+0.1
ABID97_RS12420	N.D.
ABID97_RS15750	+0.1
ABID97_RS18615	-0.1
ABID97_RS18775	+0.4
ABID97_RS20240	-0.1
ABID97_RS24190	-0.2
ABID97_RS25195	+0.5
ABID97_RS26575	N.D.
ABID97_RS27835	+0.0
ABID97_RS28230	-0.4
ABID97_RS28270	-1.0
ABID97_RS28430	-0.2
Benzoyl-CoA 3-monooxygenase: benzoyl-CoA + NADPH + dioxygen + H+→3-hydroxybenzoyl-CoA + NADP+ + H2O (EC 1.14.13.58)
No genes
3-hydroxybenzoyl-CoA + a reduced two electron carrier + dioxygen→gentisate + an oxidized electron carrier + coenzyme A + H+
No genes
Gentisate 1,2-dioxygenase: gentisate + dioxygen→3-maleylpyruvate + H+ (EC 1.13.11.4)
ABID97_RS04255	+0.5
ABID97_RS18810	+0.2
Maleylpyruvate isomerase: 3-maleylpyruvate→3-fumarylpyruvate (EC 5.2.1.4)
No genes
3-fumarylpyruvate + H2O→fumarate + pyruvate + H+ (EC 3.7.1.20)
ABID97_RS04260	-0.5
ABID97_RS12395	+0.3
ABID97_RS20690	-0.2

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information