MetaCyc Pathway: L-methionine biosynthesis IV in Escherichia coli BW25113

Reactions and Genes	D-Glucuronic Acid (C)
Aspartate kinase: L-aspartate + ATP→L-aspartyl-4-phosphate + ADP (EC 2.7.2.4)
b0002 (thrA)	-3.5
b3940 (metL)	-0.5
b4024 (lysC)	-1.2
Aspartate-semialdehyde dehydrogenase (in reverse): L-aspartyl-4-phosphate + NADPH + H+→L-aspartate 4-semialdehyde + NADP+ + phosphate (EC 1.2.1.11)
b2319 (usg)	-0.3
b3433 (asd)	N.D.
L-aspartate 4-semialdehyde + hydrogen sulfide + 2 H+ + 2 a reduced ferredoxin [iron-sulfur] cluster→L-homocysteine + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O (EC 2.8.1.16)
No genes
L-homocysteine + Coα-[α-(5-hydroxybenzimidazolyl)]-Coβ-methylcob(III)amide-[MtrA protein]→L-methionine + Coα-[α-(5-hydroxybenzimidazolyl)]-cob(I)amide-[MtrA protein] + H+ (EC 2.1.1.M84)
No genes

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information