MetaCyc Pathway: D-fructuronate degradation in Escherichia coli BW25113

Reactions and Genes	D-Glucuronic Acid (C)
Fructuronate reductase (in reverse): D-fructuronate + NADH + H+→D-mannonate + NAD+ (EC 1.1.1.57)
b1542 (ydfI)	+0.2
b2172 (yeiQ)	-0.6
b4323 (uxuB)	-0.9
Mannonate dehydratase: D-mannonate→2-dehydro-3-deoxy-D-gluconate + H2O (EC 4.2.1.8)
b4322 (uxuA)	-4.2
2-dehydro-3-deoxy-D-gluconate + ATP→2-dehydro-3-deoxy-D-gluconate 6-phosphate + ADP + H+ (EC 2.7.1.178; 2.7.1.45)
b3526 (kdgK)	-4.5
2-dehydro-3-deoxy-phosphogluconate aldolase: 2-dehydro-3-deoxy-D-gluconate 6-phosphate→D-glyceraldehyde 3-phosphate + pyruvate (EC 4.1.2.14; 4.1.2.55)
b1850 (eda)	-5.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information