MetaCyc Pathway: superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis in Pseudomonas simiae WCS417

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Reactions and Genes Neomycin 0.04 mg/ml
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Phosphoglucomutase (in reverse):
D-glucopyranose 6-phosphate→α-D-glucopyranose 1-phosphate (EC 5.4.2.2)
PS417_13395 -0.6
PS417_24005 N.D.
PS417_27785 +1.7
UTP-monosaccharide-1-phosphate uridylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + UTP→UDP-α-D-glucose + diphosphate (EC 2.7.7.64; 2.7.7.9)
PS417_14065 -3.0
UDP-glucose 4-epimerase:
UDP-α-D-glucose→UDP-α-D-galactose (EC 5.1.3.2)
PS417_01385 +0.4
PS417_17360 +0.0
PS417_22005 +0.1
PS417_02315 N.D.
UDP-glucose 6-dehydrogenase:
UDP-α-D-glucose + 2 NAD+ + H2O→UDP-α-D-glucuronate + 2 NADH + 3 H+ (EC 1.1.1.22)
PS417_13820 -3.2
UDP-galactopyranose mutase:
UDP-α-D-galactose→UDP-α-D-galactofuranose (EC 5.4.99.9)
No genes
UDP-glucuronate 4-epimerase:
UDP-α-D-glucuronate→UDP-α-D-galacturonate (EC 5.1.3.6)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information