MetaCyc Pathway: autoinducer AI-2 degradation in Escherichia coli BW25113

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Reactions and Genes a-Ketoglutaric (C)
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autoinducer 2 + ATP→(2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H+ (EC 2.7.1.189)
b1511 (ydeV) +0.4
(2S)-2-hydroxy-3,4-dioxopentyl phosphate→3-hydroxy-2,4-dioxopentyl phosphate (EC 5.3.1.32)
b1518 (lsrG) -0.4
3-hydroxy-2,4-dioxopentyl phosphate + coenzyme A→glycerone phosphate + acetyl-CoA (EC 2.3.1.245)
b1517 (lsrF) -1.1

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information