MetaCyc Pathway: superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) in Pseudomonas simiae WCS417

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Reactions and Genes A22 0.16 mg/ml
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NAD(+) kinase:
NAD+ + ATP→NADP+ + ADP + H+ (EC 2.7.1.23; 2.7.1.M29)
PS417_12370 N.D.
Aldehyde dehydrogenase (NADP(+)):
NADP+ + an aldehyde + H2O→NADPH + a carboxylate + 2 H+ (EC 1.2.1.4)
PS417_11015 +0.2
PS417_14315 -0.2
Aldehyde dehydrogenase (NAD(+)):
NAD+ + an aldehyde + H2O→NADH + a carboxylate + 2 H+ (EC 1.2.1.3)
PS417_07290 -0.1
PS417_11170 +0.1
PS417_14675 -0.1
PS417_17430 +0.1
PS417_18205 +0.4
PS417_24810 -0.1
PS417_02645 +0.1
PS417_26845 +0.1
PS417_27745 -0.0
PS417_04200 +0.1
Glucose-6-phosphate dehydrogenase:
NADP+ + D-glucopyranose 6-phosphate→NADPH + 6-phospho D-glucono-1,5-lactone + H+ (EC 1.1.1.49)
PS417_12450 -0.1
PS417_22110 N.D.
Isocitrate dehydrogenase (NADP(+)):
NADP+ + D-threo-isocitrate→NADPH + 2-oxoglutarate + CO2 (EC 1.1.1.42)
PS417_16525 -0.1
PS417_16530 N.D.
Aldehyde dehydrogenase (NADP(+)):
NADP+ + acetaldehyde + H2O→NADPH + acetate + 2 H+ (EC 1.2.1.4)
PS417_11015 +0.2
PS417_14315 -0.2
NADH kinase:
NADH + ATP→NADPH + ADP + H+ (EC 2.7.1.86; 2.7.1.M29)
No genes
NADH[in] + H+[in] + a ubiquinone→NAD+[in] + a ubiquinol (EC 1.6.5.9)
PS417_12265 +0.1
PS417_03855 -1.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information