MetaCyc Pathway: L-ornithine biosynthesis I in Pseudomonas simiae WCS417

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Reactions and Genes Carbon source L-Ornithine 5 mM
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Amino-acid N-acetyltransferase:
L-glutamate + acetyl-CoA→N-acetyl-L-glutamate + coenzyme A + H+ (EC 2.3.1.1)
PS417_22535 +0.1
PS417_27195 +0.2
PS417_28175 -0.1
Acetylglutamate kinase:
N-acetyl-L-glutamate + ATP→N-acetylglutamyl-phosphate + ADP (EC 2.7.2.8)
PS417_27790 N.D.
N-acetyl-gamma-glutamyl-phosphate reductase (in reverse):
N-acetylglutamyl-phosphate + NADPH + H+→N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate (EC 1.2.1.38)
PS417_25660 N.D.
Acetylornithine transaminase (in reverse):
N-acetyl-L-glutamate 5-semialdehyde + L-glutamate→N-acetyl-L-ornithine + 2-oxoglutarate (EC 2.6.1.11)
PS417_08025 +0.3
PS417_21710 -1.9
PS417_25950 +0.1
Acetylornithine deacetylase:
N-acetyl-L-ornithine + H2O→L-ornithine + acetate (EC 3.5.1.16)
PS417_18910 +0.2
PS417_27200 -0.0

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information