MetaCyc Pathway: TCA cycle VIII (Chlamydia) in Pseudomonas putida KT2440

Reactions and Genes	L-Leucine (C)
2-oxoglutarate + coenzyme A + NAD+→succinyl-CoA + CO2 + NADH (EC 1.2.1.105)
No genes
Succinate--CoA ligase (ADP-forming) (in reverse): succinyl-CoA + ADP + phosphate→succinate + ATP + coenzyme A (EC 6.2.1.5)
PP_4185	N.D.
PP_4186	N.D.
Succinate dehydrogenase (ubiquinone): succinate[in] + an electron-transfer quinone→fumarate[in] + an electron-transfer quinol (EC 1.3.5.1)
PP_4190	N.D.
PP_4191	N.D.
PP_4192	N.D.
PP_4193	N.D.
Fumarate hydratase (in reverse): fumarate + H2O→(S)-malate (EC 4.2.1.2)
PP_0897	N.D.
PP_0944	-0.2
PP_1755	-0.2
Malate dehydrogenase: (S)-malate + NAD+→oxaloacetate + NADH + H+ (EC 1.1.1.37; 1.1.1.38)
PP_0654	-0.0
PP_2835	+0.5
Aspartate transaminase (in reverse): oxaloacetate + L-glutamate→2-oxoglutarate + L-aspartate (EC 2.6.1.1)
PP_0486	+0.1
PP_0858	+0.2
PP_1109	+0.1
PP_1872	-0.2
PP_2642	-0.1
PP_2948	+0.0
PP_3544	-0.1
PP_3750	+0.1
PP_3786	+0.1
PP_4197	+1.1
PP_5275	-0.1
PP_5342	+0.0

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information