MetaCyc Pathway: L-phenylalanine degradation V in Escherichia coli BW25113

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Reactions and Genes 2-nitrobenzenesulfonyl fluoride
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Phenylalanine 4-monooxygenase:
an N10-formyltetrahydrofolate + L-phenylalanine + dioxygen→4a-hydroxy-N10-formyltetrahydrofolate + L-tyrosine (EC 1.14.16.1)
No genes
4a-hydroxytetrahydrobiopterin dehydratase:
4a-hydroxy-N10-formyltetrahydrofolate→an N10-formyl-7,8-dihydrofolate + H2O (EC 4.2.1.96)
No genes
6,7-dihydropteridine reductase (in reverse):
an N10-formyl-7,8-dihydrofolate + NADH + H+→an N10-formyltetrahydrofolate + NAD+ (EC 1.5.1.34)
b0578 (nfnB) +2.7

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information