MetaCyc Pathway: dTDP-N-acetylviosamine biosynthesis in Escherichia coli BW25113

Add experiment(s):


Reactions and Genes Trimethoprim 0.0025 mM
remove
Glucose-1-phosphate thymidylyltransferase:
α-D-glucopyranose 1-phosphate + H+ + dTTP→dTDP-α-D-glucose + diphosphate (EC 2.7.7.24)
b0363 (yaiP) -0.2
b2039 (rfbA) -2.4
b3789 (rffH) +0.9
dTDP-glucose 4,6-dehydratase:
dTDP-α-D-glucose→dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + H2O (EC 4.2.1.46)
b2041 (rfbB) +1.9
b3788 (rffG) +0.6
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase (in reverse):
dTDP-4-dehydro-6-deoxy-α-D-glucopyranose + L-glutamate→dTDP-viosamine + 2-oxoglutarate (EC 2.6.1.33)
No genes
dTDP-viosamine + acetyl-CoA→dTDP-N-acetylviosamine + coenzyme A + H+ (EC 2.3.1.209)
No genes

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information