MetaCyc Pathway: superpathway of guanosine nucleotides degradation (plants) in Escherichia coli BW25113
| Reactions and Genes | Trimethoprim 0.0025 mM |
|---|---|
| remove | |
| 5'-nucleotidase: GMP + H2O→guanosine + phosphate (EC 3.1.3.5) | |
| b0480 (ushA) | -0.2 |
| b2291 (yfbR) | +0.2 |
| b2744 (surE) | -1.3 |
| b3399 (yrfG) | +0.4 |
| b4055 (aphA) | -0.9 |
| b4374 (yjjG) | -2.4 |
| Guanosine deaminase: guanosine + H+ + H2O→xanthosine + ammonium (EC 3.5.4.15) | |
| No genes | |
| Purine nucleosidase: guanosine + H2O→guanine + D-ribofuranose (EC 3.2.2.1) | |
| b0030 (rihC) | -0.1 |
| b0651 (rihA) | -0.0 |
| b2162 (rihB) | +0.1 |
| Guanine deaminase: guanine + H+ + H2O→xanthine + ammonium (EC 3.5.4.3) | |
| b2883 (guaD) | +0.3 |
| Purine nucleosidase: xanthosine + H2O→xanthine + D-ribofuranose (EC 3.2.2.1) | |
| b0030 (rihC) | -0.1 |
| b0651 (rihA) | -0.0 |
| b2162 (rihB) | +0.1 |
| Xanthine dehydrogenase: xanthine + NAD+ + H2O→urate + NADH + H+ (EC 1.17.1.4) | |
| b0284 (yagR) | -0.0 |
| b0285 (yagS) | +0.2 |
| b2866 (xdhA) | -0.1 |
| b2867 (xdhB) | +0.2 |
| b2868 (xdhC) | +0.1 |
Links:
- Pathway details at MetaCyc
- Fitness data for 15 genes
- All MetaCyc pathways for Escherichia coli BW25113
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information