MetaCyc Pathway: pyrimidine deoxyribonucleosides degradation in Escherichia coli BW25113

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Reactions and Genes Trimethoprim 0.00125 mM
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Cytidine deaminase:
2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium
(EC 3.5.4.5)
b2143 (cdd) +0.4
Pyrimidine-nucleoside phosphorylase:
thymidine + phosphate→2-deoxy-α-D-ribose 1-phosphate + thymine
(EC 2.4.2.2; 2.4.2.4)
b0391 (yaiE) -0.2
b4382 (deoA) -1.5
Pyrimidine-nucleoside phosphorylase:
2'-deoxyuridine + phosphate→2-deoxy-α-D-ribose 1-phosphate + uracil
(EC 2.4.2.2; 2.4.2.3)
b3831 (udp) +0.3
b4382 (deoA) -1.5
b4384 (deoD) -0.4

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information