MetaCyc Pathway: pyrimidine deoxyribonucleosides degradation in Escherichia coli BW25113
Reactions and Genes | Trimethoprim 0.00125 mM |
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Cytidine deaminase: 2'-deoxycytidine + H+ + H2O→2'-deoxyuridine + ammonium (EC 3.5.4.5) | |
b2143 (cdd) | +0.4 |
Pyrimidine-nucleoside phosphorylase: thymidine + phosphate→2-deoxy-α-D-ribose 1-phosphate + thymine (EC 2.4.2.2; 2.4.2.4) | |
b0391 (yaiE) | -0.2 |
b4382 (deoA) | -1.5 |
Pyrimidine-nucleoside phosphorylase: 2'-deoxyuridine + phosphate→2-deoxy-α-D-ribose 1-phosphate + uracil (EC 2.4.2.2; 2.4.2.3) | |
b3831 (udp) | +0.3 |
b4382 (deoA) | -1.5 |
b4384 (deoD) | -0.4 |
Links:
Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information