MetaCyc Pathway: L-tryptophan degradation X (mammalian, via tryptamine) in Agrobacterium fabrum C58

Add experiment(s):


Reactions and Genes N-alpha-Acetyl-L-glutamate (C)
remove
L-tryptophan + H+→tryptamine + CO2 (EC 4.1.1.105; 4.1.1.28)
No genes
Monoamine oxidase:
tryptamine + dioxygen + H2O→(indol-3-yl)acetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.4)
No genes
Indole-3-acetaldehyde reductase (NADPH) (in reverse):
(indol-3-yl)acetaldehyde + NADPH + H+→(indol-3-yl)ethanol + NADP+ (EC 1.1.1.191; 1.1.1.2)
Atu2022 +0.2
Aldehyde dehydrogenase (NAD(+)):
(indol-3-yl)acetaldehyde + NAD+ + H2O→(indol-3-yl)acetate + NADH + 2 H+ (EC 1.2.1.3)
Atu2139 +0.0
Atu2224 -2.1
Atu3401 +0.1
Atu3403 -0.3
Atu3950 -0.1
Atu3959 +0.0
Atu4153 -0.1
Atu4241 +0.0
Atu4849 +0.1
Atu5228 N.D.

Links:

Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information