MetaCyc Pathway: fatty acid salvage in Escherichia coli BW25113

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Reactions and Genes LB Anaerobic with Vancomycin Hydrochloride from Streptomyces orientalis 0.00003125 mM
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Butyrate--CoA ligase:
decanoate + ATP + coenzyme A→decanoyl-CoA + AMP + diphosphate
(EC 6.2.1.2; 6.2.1.3)
b1805 (fadD) +1.3
decanoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-dec-2-enoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
b1695 (b1695) +0.1
b4187 (aidB) -0.2
Long-chain-enoyl-CoA hydratase (in reverse):
(2E)-dec-2-enoyl-CoA + H2O→(S)-3-hydroxydecanoyl-CoA
(EC 4.2.1.74)
b2341 (yfcX) -0.5
b3846 (fadB) -0.2
3-hydroxyacyl-CoA dehydrogenase:
(S)-3-hydroxydecanoyl-CoA + NAD+→3-oxodecanoyl-CoA + NADH + H+
(EC 1.1.1.35)
b2341 (yfcX) -0.5
b3846 (fadB) -0.2
Acetyl-CoA C-acyltransferase (in reverse):
3-oxodecanoyl-CoA + coenzyme A→octanoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
b1397 (paaJ) +0.1
b2224 (atoB) -0.2
b2342 (yfcY) -0.1
b2844 (yqeF) +0.4
b3845 (fadA) -0.1
octanoyl-CoA + a malonyl-[acp] + H+→a 3-oxodecanoyl-[acp] + CO2 + coenzyme A (EC 2.3.1.207)
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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information