MetaCyc Pathway: L-phenylalanine degradation IV (mammalian, via side chain) in Pseudomonas simiae WCS417

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Reactions and Genes soil sample 4; outgrowth in LB
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Aromatic-L-amino-acid decarboxylase:
L-phenylalanine + H+→2-phenylethylamine + CO2 (EC 4.1.1.28; 4.1.1.53)
No genes
Aspartate transaminase:
L-phenylalanine + 2-oxoglutarate→3-phenyl-2-oxopropanoate + L-glutamate (EC 2.6.1.1; 2.6.1.27; 2.6.1.57)
PS417_08130 -0.6
PS417_08560 -0.1
PS417_09070 +0.5
PS417_09120 -0.2
PS417_11840 +0.1
PS417_12775 +0.0
PS417_12985 -0.9
PS417_13545 +0.6
PS417_14865 -0.1
PS417_15040 -0.3
PS417_15990 -0.4
PS417_18690 +1.8
PS417_19025 +0.1
PS417_19385 -0.0
PS417_19910 +0.3
PS417_21030 +0.5
PS417_21275 +3.1
PS417_23120 -0.1
PS417_23365 +0.1
PS417_27730 +0.1
PS417_28165 +0.2
PS417_04425 -0.4
4-hydroxyphenylpyruvate dioxygenase:
3-phenyl-2-oxopropanoate + dioxygen→(2-hydroxyphenyl)acetate + CO2 (EC 1.13.11.27)
PS417_14005 -0.7
PS417_24445 -0.0
Indolelactate dehydrogenase (in reverse):
3-phenyl-2-oxopropanoate + NADH + H+→(R)-3-(phenyl)lactate + NAD+ (EC 1.1.1.110)
No genes
Primary-amine oxidase:
2-phenylethylamine + dioxygen + H2O→phenylacetaldehyde + ammonium + hydrogen peroxide (EC 1.4.3.21; 1.4.3.4)
No genes
Phenylacetaldehyde dehydrogenase:
phenylacetaldehyde + NAD+ + H2O→phenylacetate + NADH + 2 H+ (EC 1.2.1.39)
PS417_17430 +0.5
PS417_17930 +0.2
PS417_24810 -0.3
Phenylacetate--CoA ligase:
phenylacetate + ATP + coenzyme A→phenylacetyl-CoA + AMP + diphosphate (EC 6.2.1.30)
No genes
Glutamine N-phenylacetyltransferase:
phenylacetyl-CoA + L-glutamine→α-N-phenylacetyl-L-glutamine + coenzyme A + H+ (EC 2.3.1.14)
No genes
phenylacetyl-CoA + glycine→phenylacetylglycine + coenzyme A + H+ (EC 2.3.1.192)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information