MetaCyc Pathway: L-tyrosine degradation III in Agrobacterium fabrum C58

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Reactions and Genes a-Ketoglutaric (C)
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Phenylalanine(histidine) transaminase:
L-tyrosine + pyruvate→3-(4-hydroxyphenyl)pyruvate + L-alanine
(EC 2.6.1.58)
No genes
Aspartate transaminase:
L-tyrosine + 2-oxoglutarate→3-(4-hydroxyphenyl)pyruvate + L-glutamate
(EC 2.6.1.1; 2.6.1.27; 2.6.1.5; 2.6.1.57)
Atu0235 +0.0
Atu0529 -0.0
Atu1011 -0.0
Atu1589 -1.9
Atu1848 +0.1
Atu2015 -2.7
Atu2196 N.D.
Atu3612 N.D.
Atu4266 +0.3
Atu4278 +0.1
4-hydroxyphenylpyruvate decarboxylase:
3-(4-hydroxyphenyl)pyruvate + H+→(4-hydroxyphenyl)acetaldehyde + CO2
(EC 4.1.1.80)
No genes
Alcohol dehydrogenase (in reverse):
(4-hydroxyphenyl)acetaldehyde + NADH + H+→4-tyrosol + NAD+
(EC 1.1.1.1)
Atu0626 -1.6
Atu1557 -0.0
Atu1595 N.D.
Atu1670 +0.1
Atu2022 +0.1
Atu2138 -0.0
Atu2151 -0.1
Atu2528 +0.1
Atu4236 +0.1
Atu4289 -0.2
Atu5074 +0.0
Atu5138 +0.0
Atu5202 +0.1
Atu5240 N.D.

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information