MetaCyc Pathway: adipate degradation in Agrobacterium fabrum C58

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Reactions and Genes 2-6-dihydroxybenzoic (C)
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Succinate--CoA ligase (ADP-forming):
adipate + ATP + coenzyme A→adipoyl-CoA + ADP + phosphate (EC 6.2.1.5)
Atu2637 N.D.
Atu2638 N.D.
Atu4548 -2.2
adipoyl-CoA + an oxidized electron-transfer flavoprotein + H+→(2E)-5-carboxy-2-pentenoyl-CoA + a reduced electron-transfer flavoprotein (EC 1.3.8.7)
Atu0501 -1.0
Atu0732 +0.3
Atu1310 N.D.
Atu1414 -0.1
Enoyl-CoA hydratase (in reverse):
(2E)-5-carboxy-2-pentenoyl-CoA + H2O→(3S)-hydroxyadipyl-CoA (EC 4.2.1.17)
Atu0322 +0.1
Atu0503 -1.0
Atu0733 +0.2
Atu1417 -0.2
Atu3481 -0.1
Atu3505 -0.1
3-hydroxyacyl-CoA dehydrogenase:
(3S)-hydroxyadipyl-CoA + NAD+→3-oxoadipoyl-CoA + NADH + H+ (EC 1.1.1.35)
Atu0503 -1.0
Atu1415 -0.3
3-oxoadipyl-CoA thiolase (in reverse):
3-oxoadipoyl-CoA + coenzyme A→succinyl-CoA + acetyl-CoA (EC 2.3.1.174)
Atu4549 -2.5

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information