MetaCyc Pathway: 3,4,6-trichlorocatechol degradation in Agrobacterium fabrum C58

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Reactions and Genes 2-6-dihydroxybenzoic (C)
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3,4,6-trichlorocatechol + dioxygen→2,3,5-trichloro-cis,cis-muconate + H+ (EC 1.13.11.M6)
No genes
2,3,5-trichloro-cis,cis-muconate + H+→2-chloro-2-(2,4-dichloro-5-oxofuran-2-yl)acetate
No genes
2-chloro-2-(2,4-dichloro-5-oxofuran-2-yl)acetate→2,5-dichloro-trans-dienelactone + chloride + H+ (spontaneous)
No genes
Carboxymethylenebutenolidase:
2,5-dichloro-trans-dienelactone + H2O→2,5-dichloromaleylacetate + H+
(EC 3.1.1.45)
Atu0627 -0.1
Maleylacetate reductase (in reverse):
2,5-dichloromaleylacetate + NAD(P)H + H+→2,5-dichloro-3-oxoadipate + NAD(P)+
(EC 1.3.1.32)
No genes
2,5-dichloro-3-oxoadipate→5-chloromaleylacetate + chloride + H+ (spontaneous)
No genes
Maleylacetate reductase (in reverse):
5-chloromaleylacetate + NAD(P)H + H+→5-chloro-3-oxoadipate + NAD(P)+
(EC 1.3.1.32)
No genes
5-chloro-3-oxoadipate→2-maleylacetate + chloride + H+ (spontaneous)
No genes
Maleylacetate reductase (in reverse):
2-maleylacetate + NAD(P)H + H+→3-oxoadipate + NAD(P)+
(EC 1.3.1.32)
Atu2528 -1.3

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information