MetaCyc Pathway: 4-hydroxybenzoate biosynthesis III (plants) in Agrobacterium fabrum C58

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Reactions and Genes 4-Hydroxybenzoic Acid (C)
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4-coumarate--CoA ligase:
4-coumarate + ATP + coenzyme A→(E)-4-coumaroyl-CoA + AMP + diphosphate
(EC 6.2.1.12)
No genes
(E)-4-coumaroyl-CoA + H2O→3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA (EC 4.1.2.61)
Atu1417 -0.3
3-hydroxyacyl-CoA dehydrogenase:
3S-(4-hydroxyphenyl)-3-hydroxy-propanoyl-CoA + NAD+→3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + NADH + H+
(EC 1.1.1.35)
Atu0503 -1.1
Atu1415 +0.1
Acetyl-CoA C-acyltransferase (in reverse):
3-(4-hydroxyphenyl)-3-oxo-propanoyl-CoA + coenzyme A→4-hydroxybenzoyl-CoA + acetyl-CoA
(EC 2.3.1.16)
Atu0502 -1.9
Atu2769 +0.0
Atu3475 -0.1
Atu4549 -2.9
Atu4823 +0.2
4-hydroxybenzoyl-CoA thioesterase:
4-hydroxybenzoyl-CoA + H2O→4-hydroxybenzoate + coenzyme A + H+
(EC 3.1.2.23)
No genes

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Candidate genes for each reaction are identified from best hits to MetaCyc; by matching EC numbers (which are assigned by TIGRFam, SEED, or best hits to KEGG); or by matching SEED roles to KEGG reactions to MetaCyc reactions. See the "Protein" tab of each gene for more information